Clone Number: 10456
Host: Mouse Clonality: Recombinant Monoclonal
Applications： FC
Reactivity: Human
Synonyms: MOX1, MOX2, My033
Shipping: Ambient temperature
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| Isotype | IgG1 |
| Conjugate | Unconjugated |
| Synonyms | MOX1, MOX2, My033 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| FC | 1:50 - 1:100 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
CD200 (OX2) and its receptor CD200R (OX2R) are membrane glycoprotein members of the Ig superfamily. CD200 is expressed by a range of cells, including neurons, epithelial cells, endothelial cells, fibroblasts, and lymphoid cells, while its receptor, CD200R, is found on myeloid and T cells. Interaction between CD200 and CD200R downregulates macrophage function and plays a role in immunosuppression and regulation of anti-tumor immune responses.
Cellular location
Cell membrane
| FC | |
|---|---|
|
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Cell line: SK-MEL-28 |
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Cell line: Jurkat (Negative cell line) |
Research Use
For research use only, not for use in diagnostic procedures.
