Background
CD49a is a receptor for laminin and collagen. It recognizes the proline- hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage- dependent, negative regulation of EGF-stimulated cell growth.
Cellular location
Membrane
Clone Number: 11649
Host: Mouse Clonality: Recombinant Monoclonal
Applications： FC
Reactivity: Human
Synonyms: Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD49a, ITGA1
Shipping: Ambient temperature
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| Isotype | IgG1 |
| Conjugate | Unconjugated |
| Synonyms | Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD49a, ITGA1 |
| UniProt ID | |
| Immunogen | Synthetic peptide derived from human integrin alpha 1 |
| MW (kDa) | / |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| FC | 1:50 - 1:100 | Human |
| Purity | Protein G purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
CD49a is a receptor for laminin and collagen. It recognizes the proline- hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage- dependent, negative regulation of EGF-stimulated cell growth.
Cellular location
Membrane
| FC | |
|---|---|
|
|
Cell line: HeLa |
Research Use
For research use only, not for use in diagnostic procedures.