Clone Number: 11521
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： WB ICC/IF
Reactivity: Human
Synonyms: GRP-75, PBP74, MOT, HSPA9, HSPA9B, mt-HSP70
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | GRP-75, PBP74, MOT, HSPA9, HSPA9B, mt-HSP70 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:1000 | Human |
| ICC/IF | 1:50 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging.
Cellular location
Mitochondrion, Nucleus, Secreted
| WB | |
|---|---|
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Blocking buffer: 5% NFDM/TBST |
| ICC/IF | |
|---|---|
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Cell line: MCF7 |
Research Use
For research use only, not for use in diagnostic procedures.
