Clone Number: JRMR-10533-4
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： WB ICC/IF IP
Reactivity: Human, Monkey
Synonyms: GSK3A
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | GSK3A |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:1000 | Human, Monkey |
| ICC/IF | 1:50 | Human |
| IP | 1:25 - 1:50 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Glycogen synthase kinase-3 alpha that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. And contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.
Cellular location
Cytoplasm
| WB | |
|---|---|
|
|
Blocking buffer: 5% NFDM/TBST |
| ICC/IF | |
|---|---|
|
|
Cell line: HeLa |
| IP | |
|---|---|
|
|
IP of HeLa cells extracts |
Research Use
For research use only, not for use in diagnostic procedures.
