Clone Number: 11990
Host: Mouse Clonality: Recombinant Monoclonal
Applications： WB ICC/IF
Reactivity: Human
Synonyms: Mitochondrial NAD-dependent malic enzyme, NAD-ME, Malic enzyme 2
Shipping: Ambient temperature
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| Isotype | IgG2a |
| Conjugate | Unconjugated |
| Synonyms | Mitochondrial NAD-dependent malic enzyme, NAD-ME, Malic enzyme 2 |
| UniProt ID | |
| Immunogen | Synthetic peptide derived from human malic enzyme 2 |
| MW (kDa) | 56 |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:2000 | Human |
| ICC/IF | 1:50 | Human |
| Purity | Protein G purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
ME2(malic enzyme 2) is also named as NAD-ME and belongs to the malic enzymes family. ME1, ME2 are important for NADPH production, lipogenesis and glutamine metabolism, but ME2 has a more profound effect. ME2 is a genome-coded mitochondrial enzyme that converts malate to pyruvate and is involved in neuronal synthesis of the neurotransmitter γ-aminobutyric acid (GABA).
Cellular location
Mitochondrion
| WB | |
|---|---|
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Blocking buffer: 5% NFDM/TBST |
| ICC/IF | |
|---|---|
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Cell line: HeLa |
Research Use
For research use only, not for use in diagnostic procedures.
