Clone Number: JRMR-10547-66
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： ICC/IF FC
Reactivity: Human
Synonyms: CDC2, CDC28A, CDKN1, P34CDC2
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | CDC2, CDC28A, CDKN1, P34CDC2 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| ICC/IF | 1:50 | Human |
| FC | 1:50 - 1:100 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis.
Cellular location
Nucleus, Cytoplasm
| ICC/IF | |
|---|---|
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Cell line: HeLa |
| FC | |
|---|---|
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Cell line: Jurkat |
Research Use
For research use only, not for use in diagnostic procedures.
