Clone Number: JRMR-10547-66
Host: Rabbit Clonality: Recombinant Monoclonal
Applications: ICC/IF FC
Reactivity: Human
Synonyms: CDC2, CDC28A, CDKN1, P34CDC2
Shipping: Ambient temperature
Order online or send purchase order to info@ptmbio.com
Isotype | IgG |
Conjugate | Unconjugated |
Synonyms | CDC2, CDC28A, CDKN1, P34CDC2 |
UniProt ID | |
Immunogen | |
MW (kDa) | |
Specificity |
Applications | Dilution | Recommended Species |
---|---|---|
ICC/IF | 1:50 | Human |
FC | 1:50 - 1:100 | Human |
Purity | Protein A purified |
Constituents | PBS, Glycerol, BSA |
Storage | Store at -20°C. Avoid freeze/thaw cycles. |
Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis.
Cellular location
Nucleus, Cytoplasm
ICC/IF | |
---|---|
![]() |
Cell line: HeLa |
FC | |
---|---|
![]() |
Cell line: Jurkat |
Research Use
For research use only, not for use in diagnostic procedures.