Clone Number: JRMR-10317-78
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： WB ICC/IF FC
Reactivity: Human, Mouse, Rat
Synonyms: p18, CFL1
Shipping: Ambient temperature
Order online or send purchase order to info@ptmbio.com
| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | p18, CFL1 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:2000 | Human, Mouse, Rat |
| ICC/IF | 1:50 | Human |
| FC | 1:50 - 1:100 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics. Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells.
Cellular location
Cytoskeleton, Nucleus
| WB | |
|---|---|
|
|
Blocking buffer: 5% NFDM/TBST |
|
|
Blocking buffer: 5% NFDM/TBST |
| ICC/IF | |
|---|---|
|
|
Cell line: HeLa |
|
|
Cell line: SW480 |
| FC | |
|---|---|
|
|
Cell line: HeLa |
Research Use
For research use only, not for use in diagnostic procedures.
