Clone Number: JRMR-114
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： IHC-P
Reactivity: Human, Mouse, Rat
Synonyms: ERCC-1
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | ERCC-1 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| IHC-P | 1:200 - 1:1000 | Human, Mouse, Rat |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure.
Cellular location
Nucleus
| IHC-P | |
|---|---|
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Tissue: Human colon cancer |
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Tissue: Human lung squamous carcinoma |
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Tissue: Mouse colon |
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Tissue: Rat colon |
Research Use
For research use only, not for use in diagnostic procedures.
