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Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner
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Year
2023
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Journal
CELL RESEARCH
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Authors
Liao Long, et al.
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Applications
Unspecified
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Reactivity
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Glutarate regulates T cell metabolism and anti-tumour immunity
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Year
2023
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Journal
Nature Metabolism
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Authors
Minogue Eleanor, et al.
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Applications
Unspecified
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Reactivity
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Histone malonylation is regulated by SIRT5 and KAT2A
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Year
2023
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Journal
iScience
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Authors
Ran Zhang, et al.
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Applications
Unspecified
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Reactivity
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Pentylenetetrazole-Induced Seizures Are Increased after Kindling, Exhibiting Vitamin-Responsive Correlations to the Post-Seizures Behavior, Amino Acids Metabolism and Key Metabolic Regulators in the Rat Brain
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Year
2023
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Authors
Vasily A. Aleshin, et al.
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Applications
Unspecified
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Reactivity
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Hexachlorocyclohexane impairs human sperm motility by affecting lysine glutarylation and mitochondrial functions
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Year
2023
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Journal
FOOD AND CHEMICAL TOXICOLOGY
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Authors
Liu Yang, et al.
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Applications
Unspecified
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Reactivity
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Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain
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Year
2022
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Authors
Artem V. Artiukhov, et al.
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Applications
Unspecified
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Reactivity
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Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
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Year
2022
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Dhaval P. Bhatt, et al.
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Applications
Unspecified
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Reactivity
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Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation.
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Year
2022
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Journal
Frontiers in Medicine
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Authors
Alexandra I. Boyko, et al.
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Applications
Unspecified
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Reactivity
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Preparation of Affinity Purified Antibodies against ε-Glutaryl-Lysine Residues in Proteins for Investigation of Glutarylated Proteins in Animal Tissues
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Year
2021
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Journal
Biomolecules
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Authors
Artem V. Artiukhov, et al.
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Applications
Unspecified
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Reactivity
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Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome
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Year
2021
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
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Authors
Jessica N. Peoples, et al.
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Applications
Unspecified
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Reactivity
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Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells
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Year
2021
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Journal
FEBS Open Bio
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Authors
Liang Meng, et al.
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Applications
Unspecified
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Reactivity
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Skeletal muscle of torpid Richardson's ground squirrels (Urocitellus richardsonii) exhibits a less active form of citrate synthase associated with lowered lysine succinylation
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Year
2021
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Journal
CRYOBIOLOGY
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Authors
Stuart R. Green, et al.
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Applications
Unspecified
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Reactivity
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Regulation of the α-ketoglutarate dehydrogenasecomplex during hibernation in a small mammal, the Richardson's ground squirrel (Urocitellus richardsonii)
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Year
2020
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Journal
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
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Authors
Stuart R. Green, et al.
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Applications
Unspecified
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Reactivity
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Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas
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Year
2019
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Journal
PLOS BIOLOGY
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Authors
WenChao Gao, et al.
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Applications
Unspecified
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Reactivity
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Lysine glutarylation in human sperm is associated with progressive motility
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Year
2019
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Journal
HUMAN REPRODUCTION
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Authors
Cheng Yi-min, et al.
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Applications
Unspecified
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Reactivity
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Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy
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Year
2019
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Journal
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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Authors
Hadi R. Ali, et al.
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Applications
Unspecified
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Reactivity
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Characterization of the Sperm Proteome and Reproductive Outcomes with in Vitro, Fertilization after a Reduction in Male Ejaculatory Abstinence Period *
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Year
2019
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Zi-Qi Shen, et al.
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Applications
Unspecified
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Reactivity
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OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer
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Year
2019
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Journal
EXPERIMENTAL CELL RESEARCH
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Authors
Xin Lu, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
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Year
2019
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Journal
PLoS One
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Authors
Mengli Zhang, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner
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Year
2018
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Journal
Nature Communications
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Authors
Wang Yun-Qian, et al.
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Applications
Unspecified
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Reactivity
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SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell ProliferationDesuccinylation of SHMT2 by SIRT5 Promotes Tumor Cell Growth
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Year
2018
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Journal
CANCER RESEARCH
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Authors
Yang Xin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice
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Year
2018
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Journal
EBioMedicine
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
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Year
2018
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Journal
Molecular Oncology
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Authors
Liang Shi, et al.
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Applications
Unspecified
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Reactivity
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CPT1A‐mediated succinylation of S100A10 increases human gastric cancer invasion
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Year
2018
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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Authors
Chao Wang, et al.
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Applications
Unspecified
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Reactivity
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Purification of carbamoyl phosphate synthetase 1 (CPS1) from wood frog (Rana sylvatica) liver and its regulation in response to ice-nucleation and subsequent whole-body freezing
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Year
2018
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Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
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Authors
Green Stuart R, et al.
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Applications
Unspecified
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Reactivity
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Characterization of histone acylations links chromatin modifications with metabolism
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Year
2017
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Journal
Nature Communications
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Authors
Simithy Johayra, et al.
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Applications
Unspecified
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Reactivity
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Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function
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Year
2016
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Sadhukhan Sushabhan, et al.
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Applications
Unspecified
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Reactivity
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NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice
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Year
2016
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Journal
Cell Reports
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Authors
Jonathan B. Lin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense
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Year
2016
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Journal
EMBO REPORTS
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Authors
Lisha Zhou, et al.
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Applications
Unspecified
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Reactivity
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Prediction of Protein Lysine Acylation by Integrating Primary Sequence Information with Multiple Functional Features
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Year
2016
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
