Clone Number: 13237
Host: Mouse Clonality: Recombinant Monoclonal
Applications： WB IHC-P
Reactivity: Human, Mouse, Rat
Synonyms: KAT1
Shipping: Ambient temperature
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| Isotype | IgG1/kappa |
| Conjugate | Unconjugated |
| Synonyms | KAT1 |
| UniProt ID | |
| Immunogen | Recombinant human HAT1 fragment |
| MW (kDa) | 50 |
| Specificity | Anti-HAT1 Mouse mAb recognizes endogeneous level of HAT1 protein. |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:1000 | Human, Mouse, Rat |
| IHC-P | 1:50 - 1:100 | Human, Mouse, Rat |
| Purity | Protein G purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Acetylates soluble but not nucleosomal histone H4 at'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage
Cellular location
Nucleus, Cytoplasm
| WB | |
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Blocking buffer: 5% NFDM/TBST |
| IHC-P | |
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Tissue: Human colon cancer |
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Tissue: Mouse stomach |
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Tissue: Rat testis |
Research Use
For research use only, not for use in diagnostic procedures.
