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Nucleolin Malonylation as a Nuclear-Cytosol Signal Exchange Mechanism to Drive Cell Proliferation in Hepatocarcinoma by Enhancing AKT Translation
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Year
2024
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Liang Sun, et al.
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Applications
Unspecified
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Reactivity
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Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation
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Year
2024
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Journal
Theranostics
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Authors
Xiao-Yi Xiong, et al.
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Applications
Unspecified
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Lysine 2-hydroxyisobutyrylation proteomics analyses reveal the regulatory mechanism of CaMYB61-CaAFR1 module in regulating stem development in Capsicum annuum L.
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Year
2024
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Journal
PLANT JOURNAL
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Authors
Qing Li, et al.
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Applications
Unspecified
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Reactivity
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Protein acylations induced by a ketogenic diet demonstrate diverse patterns depending on organs and differ between histones and global proteins
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Year
2024
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Journal
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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Authors
Minami Ito, et al.
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Applications
Unspecified
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Reactivity
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Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner
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Year
2023
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Journal
CELL RESEARCH
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Authors
Liao Long, et al.
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Applications
Unspecified
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Reactivity
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De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics
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Year
2023
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Journal
Nature Communications
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Authors
Rowland Leslie A., et al.
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Applications
Unspecified
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Histone malonylation is regulated by SIRT5 and KAT2A
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Year
2023
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Journal
iScience
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Authors
Ran Zhang, et al.
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Applications
Unspecified
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Reactivity
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The Deacylase Sirtuin 5 Reduces Malonylation in Non-mitochondrial Metabolic Pathways in Diabetic Kidney Disease
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Year
2023
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Judy Baek, et al.
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Applications
Unspecified
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Decreased liver B vitamin-related enzymes as a metabolic hallmark of cancer cachexia
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Year
2023
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Journal
Nature Communications
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Authors
Kojima Yasushi, et al.
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Applications
Unspecified
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Reactivity
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Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice
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Year
2023
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Xuechun Yang, et al.
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Applications
Unspecified
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Reactivity
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A chemical catalyst enabling histone acylation with endogenous acyl-CoA
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Year
2023
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Journal
Nature Communications
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Authors
Habazaki Misuzu, et al.
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Applications
Unspecified
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Reactivity
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VDAC2 malonylation participates in sepsis-induced myocardial dysfunction via mitochondrial-related ferroptosis
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Year
2023
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Journal
International Journal of Biological Sciences
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Authors
She Han, et al.
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Applications
Unspecified
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Reactivity
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Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program
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Year
2023
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Journal
Cell Reports
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Authors
Adilson Guilherme, et al.
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Applications
Unspecified
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Reactivity
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LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer
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Year
2023
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Journal
CELL DEATH AND DIFFERENTIATION
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Authors
Shi Liang, et al.
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Applications
Unspecified
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Reactivity
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Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
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Year
2023
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Journal
Cell Reports
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Authors
Huanyi Cao, et al.
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Applications
Unspecified
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Reactivity
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The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease
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Year
2023
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Judy Baek, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin5 protects colorectal cancer from DNA damage by keeping nucleotide availability
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Year
2022
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Journal
Nature Communications
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Authors
Wang Hao-Lian, et al.
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Applications
Unspecified
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Reactivity
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Lysine Acylation Modification Landscape of Brucella abortus Proteome and its Virulent Proteins.
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Year
2022
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Journal
Frontiers in Cell and Developmental Biology
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Authors
Zhang X, et al.
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Applications
Unspecified
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Reactivity
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Malonylome analysis uncovers the association of lysine malonylation with metabolism and acidic stress in pathogenic Mycobacterium tuberculosis
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Year
2022
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Journal
MICROBIOLOGICAL RESEARCH
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Authors
Jing Bi, et al.
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Applications
Unspecified
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Global profiling of protein lysine malonylation in mouse cardiac hypertrophy
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Year
2022
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Journal
Journal of Proteomics
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Authors
Li-Fei Wu, et al.
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Applications
Unspecified
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Reactivity
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The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A
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Year
2022
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Journal
BIOCHEMISTRY
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Authors
Ananya Anmangandla, et al.
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Applications
Unspecified
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Reactivity
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Lysine Acylation Modification Landscape of Brucella abortus Proteome and its Virulent Proteins
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Year
2022
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Journal
Frontiers in Cell and Developmental Biology
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Authors
Xi Zhang, et al.
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Applications
Unspecified
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Reactivity
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Dihydroartemisinin ameliorates retinal vascular dysfunction in diabetes mellitus via the FASN/Kmal-mTOR/SREBP1 feedback loop
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Year
2021
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Journal
PHARMACOLOGICAL RESEARCH
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Authors
Chufeng Gu, et al.
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Applications
Unspecified
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Reactivity
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Metabolic Adaptation of Macrophages as Mechanism of Defense against Crystalline Silica
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Year
2021
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Journal
JOURNAL OF IMMUNOLOGY
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Authors
Marrocco Antonella, et al.
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Applications
Unspecified
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Reactivity
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Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome
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Year
2021
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
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Authors
Jessica N. Peoples, et al.
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Applications
Unspecified
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Synthesis and Evaluation of a Stable Isostere of Malonyllysine**
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Year
2021
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Journal
CHEMBIOCHEM
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Authors
Yihang Jing, et al.
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Applications
Unspecified
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Reactivity
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Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells
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Year
2021
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Journal
FEBS Open Bio
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Authors
Liang Meng, et al.
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Applications
Unspecified
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Reactivity
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Skeletal muscle of torpid Richardson's ground squirrels (Urocitellus richardsonii) exhibits a less active form of citrate synthase associated with lowered lysine succinylation
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Year
2021
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Journal
CRYOBIOLOGY
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Authors
Stuart R. Green, et al.
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Applications
Unspecified
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Reactivity
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Protein Hyperacylation Links Mitochondrial Dysfunction with Nuclear Organization
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Year
2020
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Journal
MOLECULAR CELL
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Authors
Smestad John, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose-derived mesenchymal stem cells via metabolic switching
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Year
2020
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Journal
Clinical and Translational Medicine
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Authors
Tiantong Ou, et al.
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Applications
Unspecified
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Reactivity
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Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii
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Year
2020
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Journal
Frontiers in Microbiology
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Authors
Nie Lan-Bi, et al.
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Applications
Unspecified
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Reactivity
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Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice
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Year
2020
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Journal
Scientific Reports
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Authors
Goetzman Eric S., et al.
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Applications
Unspecified
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Nucleotide-binding sites can enhance N-acylation of nearby protein lysine residues
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Year
2020
-
Journal
Scientific Reports
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Authors
James Andrew M., et al.
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Applications
Unspecified
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Reactivity
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Regulation of the α-ketoglutarate dehydrogenasecomplex during hibernation in a small mammal, the Richardson's ground squirrel (Urocitellus richardsonii)
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Year
2020
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Journal
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
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Authors
Stuart R. Green, et al.
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Applications
Unspecified
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Reactivity
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Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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Year
2019
-
Journal
MOLECULAR CELL
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Authors
GuoXiao Wang, et al.
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Applications
Unspecified
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Reactivity
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Malonylation of GAPDH is an inflammatory signal in macrophages
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Year
2019
-
Journal
Nature Communications
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Authors
Galván-Peña Silvia, et al.
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Applications
Unspecified
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Reactivity
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Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas
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Year
2019
-
Journal
PLOS BIOLOGY
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Authors
WenChao Gao, et al.
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Applications
Unspecified
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Reactivity
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Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics
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Year
2019
-
Journal
Cell Reports
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Authors
Kelsey H. Fisher-Wellman, et al.
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Applications
Unspecified
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Reactivity
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Succinylation-dependent mitochondrial translocation of PKM2 promotes cell survival in response to nutritional stress
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Year
2019
-
Journal
Cell Death & Disease
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Authors
Qi Hailong, et al.
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Applications
Unspecified
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Reactivity
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Lysine glutarylation in human sperm is associated with progressive motility
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Year
2019
-
Journal
HUMAN REPRODUCTION
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Authors
Cheng Yi-min, et al.
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Applications
Unspecified
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Reactivity
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Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy
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Year
2019
-
Journal
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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Authors
Hadi R. Ali, et al.
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Applications
Unspecified
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Reactivity
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OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer
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Year
2019
-
Journal
EXPERIMENTAL CELL RESEARCH
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Authors
Xin Lu, et al.
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Applications
Unspecified
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Reactivity
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Dose-response regulation system for improving renal injury in diabetic nephropathy by buckwheat hull flavonoids
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Year
2019
-
Journal
Journal of Functional Foods
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Authors
Yufang Tang, et al.
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Applications
Unspecified
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Reactivity
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Lysine malonylation and propionylation are prevalent in human lens proteins
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Year
2019
-
Journal
EXPERIMENTAL EYE RESEARCH
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Authors
Rooban B. Nahomi, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
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Year
2019
-
Journal
PLoS One
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Authors
Mengli Zhang, et al.
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Applications
Unspecified
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Reactivity
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Elevated lysine crotonylation and succinylation in the brains of BTBR mice
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Year
2019
-
Journal
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
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Authors
Min Wang, et al.
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Applications
Unspecified
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Reactivity
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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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Year
2018
-
Journal
Cell Metabolism
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Authors
Mariana G. Tarragó, et al.
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Applications
Unspecified
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Reactivity
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Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation
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Year
2018
-
Journal
Cell Metabolism
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Authors
Ulrike Bruning, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner
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Year
2018
-
Journal
Nature Communications
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Authors
Wang Yun-Qian, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice
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Year
2018
-
Journal
EBioMedicine
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Authors
Yipeng Du, et al.
-
Applications
Unspecified
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Reactivity
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Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products
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Year
2018
-
Journal
Cell Chemical Biology
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Authors
Jun-Yu Xu, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
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Year
2018
-
Journal
Molecular Oncology
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Authors
Liang Shi, et al.
-
Applications
Unspecified
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Reactivity
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Characterization of the Sperm Proteome and Reproductive Outcomes with in Vitro, Fertilization after a Reduction in Male Ejaculatory Abstinence Period *
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Year
2018
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Zi-Qi Shen, et al.
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Applications
Unspecified
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Reactivity
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CPT1A‐mediated succinylation of S100A10 increases human gastric cancer invasion
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Year
2018
-
Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
-
Authors
Chao Wang, et al.
-
Applications
Unspecified
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Reactivity
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LC–MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes
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Year
2018
-
Journal
Scientific Reports
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Authors
Tanabe Kana, et al.
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Applications
Unspecified
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Reactivity
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Purification of carbamoyl phosphate synthetase 1 (CPS1) from wood frog (Rana sylvatica) liver and its regulation in response to ice-nucleation and subsequent whole-body freezing
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Year
2018
-
Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
-
Authors
Green Stuart R., et al.
-
Applications
Unspecified
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Reactivity
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CPT1A-mediated succinylation of S100A10 increases human gastric cancer invasion
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Year
2018
-
Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
-
Authors
Chao Wang, et al.
-
Applications
Unspecified
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Reactivity
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LC-MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes.
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Year
2018
-
Journal
Scientific Reports
-
Authors
Kana Tanabe, et al.
-
Applications
Unspecified
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Reactivity
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Synthetic Chromatin Acylation by an Artificial Catalyst System
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Year
2017
-
Journal
Chem
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Authors
Tadashi Ishiguro, et al.
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Applications
Unspecified
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Reactivity
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A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation
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Year
2017
-
Journal
Cell Metabolism
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Authors
Gregory R. Wagner, et al.
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Applications
Unspecified
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Reactivity
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Characterization of histone acylations links chromatin modifications with metabolism
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Year
2017
-
Journal
Nature Communications
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Authors
Simithy Johayra, et al.
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Applications
Unspecified
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Reactivity
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Malonylome Analysis Reveals the Involvement of Lysine Malonylation in Metabolism and Photosynthesis in Cyanobacteria
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Year
2017
-
Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Yanyan Ma, et al.
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Applications
Unspecified
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Reactivity
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Malonylome analysis in developing rice (Oryza sativa) seeds suggesting that protein lysine malonylation is well-conserved and overlaps with acetylation and succinylation substantially
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Year
2017
-
Journal
Journal of Proteomics
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Authors
Hana Mujahid, et al.
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Applications
Unspecified
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Reactivity
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NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice
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Year
2016
-
Journal
Cell Reports
-
Authors
Jonathan B. Lin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense
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Year
2016
-
Journal
EMBO REPORTS
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Authors
Lisha Zhou, et al.
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Applications
Unspecified
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Reactivity
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Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea
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Year
2016
-
Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Jun-Yu Xu, et al.
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Applications
Unspecified
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Reactivity
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Prediction of Protein Lysine Acylation by Integrating Primary Sequence Information with Multiple Functional Features
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Year
2016
-
Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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Lysine Malonylation Is Elevated in Type 2 Diabetic Mouse Models and Enriched in Metabolic Associated Proteins *
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Year
2014
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
-
Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism
-
Year
2014
-
Journal
JOURNAL OF INHERITED METABOLIC DISEASE
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Authors
Pougovkina Olga, et al.
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Applications
Unspecified
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Reactivity
