Clone Number: 10865
Host: Mouse Clonality: Recombinant Monoclonal
Applications： WB IHC-P ICC/IF
Reactivity: Human, Mouse
Synonyms: NAD-dependent protein deacetylase sirtuin-1, SIR2L1
Shipping: Ambient temperature
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| Isotype | IgG1 |
| Conjugate | Unconjugated |
| Synonyms | NAD-dependent protein deacetylase sirtuin-1, SIR2L1 |
| UniProt ID | |
| Immunogen | Recombinant human SIRT1 fragment |
| MW (kDa) | 110 |
| Specificity | Anti-SIRT1 Mouse mAb recognizes endogenous level of SIRT1 protein. |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:2000 | Human, Mouse |
| IHC-P | 1:100 - 1:500 | Human, Mouse |
| ICC/IF | 1:50 - 1:100 | Human |
| Purity | Protein G purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
NAD-dependent protein deacetylase sirtuin-1 links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy.
Cellular location
Nucleus, Mitochondrion
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Blocking buffer: 5% NFDM/TBST |
| IHC-P | |
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Tissue: Mouse testis |
| ICC/IF | |
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Cell line: HeLa |
Research Use
For research use only, not for use in diagnostic procedures.
