Clone Number: JRMR-10436-3
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： WB IHC-P
Reactivity: Human, Mouse
Synonyms: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2, SMARCA2, BRG1-associated factor 190B (BAF190B) Probable global transcription activator SNF2L2, Protein brahma homolog (hBRM), SNF2-alpha, BAF190B, BRM, SNF2A, SNF2L2
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2, SMARCA2, BRG1-associated factor 190B (BAF190B) Probable global transcription activator SNF2L2, Protein brahma homolog (hBRM), SNF2-alpha, BAF190B, BRM, SNF2A, SNF2L2 |
| UniProt ID | |
| Immunogen | Synthetic peptide derived from human SMARCA2 |
| MW (kDa) | 181 |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500 - 1:1000 | Human |
| IHC-P | 1:50 - 1:100 | Mouse |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner.
Cellular location
Nucleus
| WB | |
|---|---|
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Blocking buffer: 5% NFDM/TBST |
| IHC-P | |
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Tissue: Mouse cerebrum |
Research Use
For research use only, not for use in diagnostic procedures.
