Clone Number: JMMR-2225
Host: Rabbit Clonality: Recombinant Monoclonal
Applications： WB IHC-P
Reactivity: Human, Mouse, Rat
Synonyms: BAF190B, SNF2A, SNF2L2
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | BAF190B, SNF2A, SNF2L2 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | 181 |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:1000 | Human |
| IHC-P | 1:500 - 1:3000 | Human, Mouse, Rat |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
SMARCA2, also named as BRM, is a transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. SMARCA2 is involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Cellular location
Nucleus
| WB | |
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Blocking buffer: 5% NFDM/TBST |
| IHC-P | |
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Tissue: Human cerebrum |
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Tissue: Human colon |
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Tissue: Mouse testis |
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Tissue: Rat kidney |
Research Use
For research use only, not for use in diagnostic procedures.
