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Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis
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Year
2024
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Journal
Cell Reports
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Authors
Xuedi Zhang, et al.
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Applications
Unspecified
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Reactivity
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Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis
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Year
2024
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Journal
Cell Metabolism
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Authors
Ruilong Liu, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin-5 Is Recruited to Hepatic Peroxisomes in Mice Fed Dodecanedioic Acid but Has Little Impact on the Peroxisomal Succinylome
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Year
2024
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Journal
Biomolecules
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Authors
Yuxun Zhang, et al.
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Applications
Unspecified
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Reactivity
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Succinylation modification-mediated upregulation of Sp1 promotes hepatocellular carcinoma cell proliferation
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Year
2024
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Journal
Discover Oncology
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Authors
Han Yehong, et al.
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Applications
Unspecified
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Reactivity
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Increased DNMT1 acetylation leads to global DNA methylation suppression in follicular granulosa cells during reproductive aging in mammals
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Year
2024
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Journal
BMC GENOMICS
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Authors
Zhao Shunran, et al.
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Applications
Unspecified
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Reactivity
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Drug repurposing: An antidiabetic drug Ipragliflozin as Mycobacterium tuberculosis sirtuin-like protein inhibitor that synergizes with anti-tuberculosis drug isoniazid
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Year
2024
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Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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Authors
Junfeng Zhen, et al.
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Applications
Unspecified
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Reactivity
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Lactylation of RNA m6A demethylase ALKBH5 promotes innate immune response to DNA herpesviruses and mpox virus
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Year
2024
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Wan Li, et al.
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Applications
Unspecified
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Reactivity
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Astragaloside IV protects renal tubular epithelial cells against oxidative stress-induced injury by upregulating CPT1A-mediated HSD17B10 lysine succinylation in diabetic kidney disease
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Year
2024
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Journal
PHYTOTHERAPY RESEARCH
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Authors
Meng Wang, et al.
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Applications
Unspecified
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Reactivity
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Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis
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Year
2024
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Journal
Nature Communications
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Authors
Li Yinzheng, et al.
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Applications
Unspecified
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Reactivity
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Thiol-Mediated Enhancement of Nε-Acetyllysine Formation in Lens Proteins
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Year
2024
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Journal
ACS Chemical Biology
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Authors
Sudipta Panja, et al.
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Applications
Unspecified
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Reactivity
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Comprehensive Proteome and Acetylome Analysis of Needle Senescence in Larix gmelinii
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Year
2024
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Authors
Xuting Zhang, et al.
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Applications
Unspecified
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Reactivity
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Lysine 2-hydroxyisobutyrylation proteomics analyses reveal the regulatory mechanism of CaMYB61-CaAFR1 module in regulating stem development in Capsicum annuum L.
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Year
2024
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Journal
PLANT JOURNAL
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Authors
Qing Li, et al.
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Applications
Unspecified
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Reactivity
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Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
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Year
2024
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Journal
iScience
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Authors
Taolin Yuan, et al.
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Applications
Unspecified
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Reactivity
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The crotonylated and succinylated proteins of jujube involved in phytoplasma-stress responses
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Year
2024
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Journal
BMC BIOLOGY
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Authors
Liman Zhang, et al.
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Applications
Unspecified
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Reactivity
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SIRT1 maintains bone homeostasis by regulating osteoblast glycolysis through GOT1
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Year
2024
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Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
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Authors
Jin Xinxin, et al.
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Applications
Unspecified
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Reactivity
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Succinylation of Park 7 Activates a Protective Metabolic Response to Acute Kidney Injury
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Year
2024
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
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Authors
Katherine Pfister, et al.
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Applications
Unspecified
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Reactivity
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Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion
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Year
2024
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Journal
Nature Chemistry
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Authors
Weyh Maria, et al.
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Applications
Unspecified
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Reactivity
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TIGAR reduces neuronal ferroptosis by inhibiting succinate dehydrogenase activity in cerebral ischemia
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Year
2024
-
Journal
FREE RADICAL BIOLOGY AND MEDICINE
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Authors
Xinxin Wang, et al.
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Applications
Unspecified
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Reactivity
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Global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar
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Year
2024
-
Journal
Journal of Proteomics
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Authors
Keqing Qiu, et al.
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Applications
Unspecified
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Reactivity
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SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23
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Year
2024
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Journal
BMC CANCER
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Authors
Wu Yongkang, et al.
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Applications
Unspecified
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Reactivity
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Sub-MIC vancomycin enhances the antibiotic tolerance of vancomycin-intermediate Staphylococcus aureus through downregulation of protein succinylation
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Year
2024
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Journal
MICROBIOLOGICAL RESEARCH
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Authors
Yi Yang, et al.
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Applications
Unspecified
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Reactivity
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Succinylated acetyl-CoA carboxylase contributes to aflatoxin biosynthesis, morphology development, and pathogenicity in Aspergillus flavus
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Year
2024
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Journal
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
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Authors
Rui Xie, et al.
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Applications
Unspecified
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Reactivity
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Acetyltransferase P300 Regulates Glucose Metabolic Reprogramming through Catalyzing Succinylation in Lung Cancer
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Year
2024
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Authors
Qingzhi Ma, et al.
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Applications
Unspecified
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Reactivity
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HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation
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Year
2023
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Journal
Cell Discovery
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Authors
Li Jialun, et al.
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Applications
Unspecified
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Reactivity
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Core-predominant gut fungus Kazachstania slooffiae promotes intestinal epithelial glycolysis via lysine desuccinylation in pigs
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Year
2023
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Journal
Microbiome
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Authors
Hu Jun, et al.
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Applications
Unspecified
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Reactivity
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SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis
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Year
2023
-
Journal
EXPERIMENTAL AND MOLECULAR MEDICINE
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Authors
Mao Jianxin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 alleviates liver ischemia/reperfusion injury by regulating mitochondrial succinylation and oxidative stress
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Year
2023
-
Journal
ANTIOXIDANTS & REDOX SIGNALING
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Authors
Prof. Jihong Yao, et al.
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Applications
Unspecified
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Reactivity
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STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma
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Year
2023
-
Journal
iScience
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Authors
Qifan Hu, et al.
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Applications
Unspecified
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Reactivity
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Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice
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Year
2023
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Xuechun Yang, et al.
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Applications
Unspecified
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Reactivity
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Comprehensive analysis of the lysine succinylome in fish oil-treated prostate cancer cells
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Year
2023
-
Journal
Life Science Alliance
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Authors
Yifan Jiang, et al.
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Applications
Unspecified
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Reactivity
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Structure–Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney Injury
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Year
2023
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
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Authors
Luohe Mou, et al.
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Applications
Unspecified
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Reactivity
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SLC25A51 promotes tumor growth through sustaining mitochondria acetylation homeostasis and proline biogenesis
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Year
2023
-
Journal
CELL DEATH AND DIFFERENTIATION
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Authors
Li Yutong, et al.
-
Applications
Unspecified
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Reactivity
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Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure
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Year
2022
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Shingo Takada, et al.
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Applications
Unspecified
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Reactivity
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GABA regulates IL-1β production in macrophages
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Year
2022
-
Journal
Cell Reports
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Authors
Jian Fu, et al.
-
Applications
Unspecified
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Reactivity
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Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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Year
2022
-
Journal
Cell Reports
-
Authors
Zilong Zheng, et al.
-
Applications
Unspecified
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Reactivity
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The freezability of Mediterranean buffalo sperm is associated with lysine succinylation and lipid metabolism
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Year
2022
-
Journal
FASEB JOURNAL
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Authors
Xi Luo, et al.
-
Applications
Unspecified
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Reactivity
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GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis
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Year
2022
-
Journal
iScience
-
Authors
Can Cao, et al.
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Applications
Unspecified
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Reactivity
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Integrated insights into the mechanisms underlying sepsis-induced myocardial depression using a quantitative global proteomic analysis
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Year
2022
-
Journal
Journal of Proteomics
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Authors
Ni Yang, et al.
-
Applications
Unspecified
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Reactivity
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First analyses of lysine succinylation proteome and overlap between succinylation and acetylation in Solenopsis invicta Buren (Hymenoptera: Formicidae)
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Year
2022
-
Journal
BMC GENOMICS
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Authors
Ye Jingwen, et al.
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Applications
Unspecified
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Reactivity
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The decrotonylase FoSir5 facilitates mitochondrial metabolic state switching in conidial germination of Fusarium oxysporum
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Year
2021
-
Journal
eLife
-
Authors
Ning Zhang, et al.
-
Applications
Unspecified
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Reactivity
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Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism
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Year
2021
-
Journal
Frontiers in Cell and Developmental Biology
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Authors
Zhou Boda, et al.
-
Applications
Unspecified
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Reactivity
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Evidence for a Negative Correlation between Human Reactive Enamine-Imine Intermediate Deaminase A (RIDA) Activity and Cell Proliferation Rate: Role of Lysine Succinylation of RIDA
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Year
2021
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
-
Authors
Luisa Siculella, et al.
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Applications
Unspecified
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Reactivity
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First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence
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Year
2021
-
Journal
Frontiers in Cellular and Infection Microbiology
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Authors
Zeng Fuyuan, et al.
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Applications
Unspecified
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Reactivity
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Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies
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Year
2021
-
Journal
Scientific Reports
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Authors
Kollenstart Leonie, et al.
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Applications
Unspecified
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Reactivity
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Global analysis of protein succinylation modification of Nostoc flagelliforme in response to dehydration
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Year
2021
-
Journal
Journal of Proteomics
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Authors
Xiaoxu Li, et al.
-
Applications
Unspecified
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Reactivity
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Malonyl-proteome profiles of Staphylococcus aureus reveal lysine malonylation modification in enzymes involved in energy metabolism
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Year
2021
-
Journal
Proteome Science
-
Authors
Shi Yanan, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose-derived mesenchymal stem cells via metabolic switching
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Year
2020
-
Journal
Clinical and Translational Medicine
-
Authors
Tiantong Ou, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis
-
Year
2019
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Kai Su Greene, et al.
-
Applications
Unspecified
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Reactivity
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Lysine glutarylation in human sperm is associated with progressive motility
-
Year
2019
-
Journal
HUMAN REPRODUCTION
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Authors
Cheng Yi-min, et al.
-
Applications
Unspecified
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Reactivity
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Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy
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Year
2019
-
Journal
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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Authors
Hadi R. Ali, et al.
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Applications
Unspecified
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Reactivity
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Protein kinase Cα mediates recovery of renal and mitochondrial functions following acute injury
-
Year
2019
-
Journal
FEBS Journal
-
Authors
Grazyna Nowak, et al.
-
Applications
Unspecified
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Reactivity
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OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer
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Year
2019
-
Journal
EXPERIMENTAL CELL RESEARCH
-
Authors
Xin Lu, et al.
-
Applications
Unspecified
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Reactivity
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Dose-response regulation system for improving renal injury in diabetic nephropathy by buckwheat hull flavonoids
-
Year
2019
-
Journal
Journal of Functional Foods
-
Authors
Yufang Tang, et al.
-
Applications
Unspecified
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Reactivity
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Succinylation Is a Gain-of-Function Modification in Human Lens αB-Crystallin
-
Year
2019
-
Journal
BIOCHEMISTRY
-
Authors
Sandip K. Nandi, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
-
Year
2019
-
Journal
PLoS One
-
Authors
Mengli Zhang, et al.
-
Applications
Unspecified
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Reactivity
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Elevated lysine crotonylation and succinylation in the brains of BTBR mice
-
Year
2019
-
Journal
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
-
Authors
Min Wang, et al.
-
Applications
Unspecified
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Reactivity
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SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell ProliferationDesuccinylation of SHMT2 by SIRT5 Promotes Tumor Cell Growth
-
Year
2018
-
Journal
CANCER RESEARCH
-
Authors
Yang Xin, et al.
-
Applications
Unspecified
-
Reactivity
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Characterization of the Sperm Proteome and Reproductive Outcomes with in Vitro, Fertilization after a Reduction in Male Ejaculatory Abstinence Period *
-
Year
2018
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
-
Authors
Zi-Qi Shen, et al.
-
Applications
Unspecified
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Reactivity
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SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell Proliferation
-
Year
2018
-
Journal
CANCER RESEARCH
-
Authors
Yang Xin, et al.
-
Applications
Unspecified
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Reactivity
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SIRT5 regulation of ammonia-induced autophagy and mitophagy
-
Year
2015
-
Journal
Autophagy
-
Authors
Lucia Polletta, et al.
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Applications
Unspecified
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Reactivity
