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HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation
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Year
2023
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Journal
Cell Discovery
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Authors
Li Jialun, et al.
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Applications
Unspecified
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Reactivity
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Core-predominant gut fungus Kazachstania slooffiae promotes intestinal epithelial glycolysis via lysine desuccinylation in pigs
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Year
2023
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Journal
Microbiome
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Authors
Hu Jun, et al.
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Applications
Unspecified
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Reactivity
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SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis
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Year
2023
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Journal
EXPERIMENTAL AND MOLECULAR MEDICINE
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Authors
Mao Jianxin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 alleviates liver ischemia/reperfusion injury by regulating mitochondrial succinylation and oxidative stress
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Year
2023
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Journal
ANTIOXIDANTS & REDOX SIGNALING
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Authors
Prof. Jihong Yao, et al.
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Applications
Unspecified
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Reactivity
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STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma
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Year
2023
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Journal
iScience
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Authors
Qifan Hu, et al.
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Applications
Unspecified
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Reactivity
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Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure
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Year
2022
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Takada Shingo, et al.
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Applications
Unspecified
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Reactivity
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GABA regulates IL-1β production in macrophages
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Year
2022
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Journal
Cell Reports
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Authors
Jian Fu, et al.
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Applications
Unspecified
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Reactivity
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Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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Year
2022
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Journal
Cell Reports
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Authors
Zilong Zheng, et al.
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Applications
Unspecified
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Reactivity
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The freezability of Mediterranean buffalo sperm is associated with lysine succinylation and lipid metabolism
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Year
2022
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Journal
FASEB JOURNAL
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Authors
Xi Luo, et al.
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Applications
Unspecified
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Reactivity
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GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis
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Year
2022
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Journal
iScience
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Authors
Can Cao, et al.
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Applications
Unspecified
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Reactivity
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Integrated insights into the mechanisms underlying sepsis-induced myocardial depression using a quantitative global proteomic analysis
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Year
2022
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Journal
Journal of Proteomics
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Authors
Ni Yang, et al.
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Applications
Unspecified
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Reactivity
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First analyses of lysine succinylation proteome and overlap between succinylation and acetylation in Solenopsis invicta Buren (Hymenoptera: Formicidae)
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Year
2022
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Journal
BMC GENOMICS
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Authors
Ye Jingwen, et al.
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Applications
Unspecified
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Reactivity
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The decrotonylase FoSir5 facilitates mitochondrial metabolic state switching in conidial germination of Fusarium oxysporum
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Year
2021
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Journal
eLife
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Authors
Ning Zhang, et al.
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Applications
Unspecified
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Reactivity
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Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism
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Year
2021
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Journal
Frontiers in Cell and Developmental Biology
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Authors
Boda Zhou, et al.
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Applications
Unspecified
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Reactivity
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Evidence for a Negative Correlation between Human Reactive Enamine-Imine Intermediate Deaminase A (RIDA) Activity and Cell Proliferation Rate: Role of Lysine Succinylation of RIDA
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Year
2021
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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Authors
Luisa Siculella, et al.
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Applications
Unspecified
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Reactivity
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First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence
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Year
2021
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Journal
Frontiers in Cellular and Infection Microbiology
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Authors
Zeng Fuyuan, et al.
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Applications
Unspecified
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Reactivity
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Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies
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Year
2021
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Journal
Scientific Reports
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Authors
Kollenstart, et al.
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Applications
Unspecified
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Reactivity
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Global analysis of protein succinylation modification of Nostoc flagelliforme in response to dehydration
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Year
2021
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Journal
Journal of Proteomics
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Authors
Xiaoxu Li, et al.
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Applications
Unspecified
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Reactivity
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Malonyl-proteome profiles of Staphylococcus aureus reveal lysine malonylation modification in enzymes involved in energy metabolism
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Year
2021
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Journal
Proteome Science
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Authors
Shi Yanan, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose-derived mesenchymal stem cells via metabolic switching
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Year
2020
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Journal
Clinical and Translational Medicine
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Authors
Tiantong Ou, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis
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Year
2019
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Greene Kai Su, et al.
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Applications
Unspecified
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Reactivity
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Lysine glutarylation in human sperm is associated with progressive motility
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Year
2019
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Journal
HUMAN REPRODUCTION
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Authors
Cheng Yi-min, et al.
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Applications
Unspecified
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Reactivity
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Defining decreased protein succinylation of failing human cardiac myofibrils in ischemic cardiomyopathy
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Year
2019
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Journal
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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Authors
Hadi R. Ali, et al.
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Applications
Unspecified
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Reactivity
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Characterization of the Sperm Proteome and Reproductive Outcomes with in Vitro, Fertilization after a Reduction in Male Ejaculatory Abstinence Period *
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Year
2019
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Zi-Qi Shen, et al.
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Applications
Unspecified
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Reactivity
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Protein kinase Cα mediates recovery of renal and mitochondrial functions following acute injury
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Year
2019
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Journal
FEBS Journal
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Authors
Grazyna Nowak, et al.
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Applications
Unspecified
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Reactivity
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OGDH mediates the inhibition of SIRT5 on cell proliferation and migration of gastric cancer
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Year
2019
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Journal
EXPERIMENTAL CELL RESEARCH
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Authors
Xin Lu, et al.
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Applications
Unspecified
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Reactivity
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Dose-response regulation system for improving renal injury in diabetic nephropathy by buckwheat hull flavonoids
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Year
2019
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Journal
Journal of Functional Foods
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Authors
Yufang Tang, et al.
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Applications
Unspecified
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Reactivity
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Succinylation Is a Gain-of-Function Modification in Human Lens αB-Crystallin
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Year
2019
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Journal
BIOCHEMISTRY
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Authors
Sandip, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress
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Year
2019
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Journal
PLoS One
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Authors
Mengli Zhang, et al.
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Applications
Unspecified
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Reactivity
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Elevated lysine crotonylation and succinylation in the brains of BTBR mice
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Year
2019
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Journal
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
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Authors
Min Wang, et al.
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Applications
Unspecified
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Reactivity
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SHMT2 Desuccinylation by SIRT5 Drives Cancer Cell ProliferationDesuccinylation of SHMT2 by SIRT5 Promotes Tumor Cell Growth
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Year
2018
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Journal
CANCER RESEARCH
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Authors
Yang Xin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 regulation of ammonia-induced autophagy and mitophagy
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Year
2015
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Journal
Autophagy
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Authors
Lucia Polletta, et al.
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Applications
Unspecified
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Reactivity
