-
Total glucosides of paeony ameliorates chemotherapy-induced neuropathic pain by suppressing microglia pyroptosis through the inhibition of KAT2A-mediated p38 pathway activation and succinylation
-
Year
2024
-
Journal
Scientific Reports
-
Authors
Chen Rong, et al.
-
Applications
Unspecified
-
Reactivity
-
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis
-
Year
2024
-
Journal
Cell Reports
-
Authors
Xuedi Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT5 mediated succinylation of SUCLA2 regulates TCA cycle dysfunction and mitochondrial damage in pancreatic acinar cells in acute pancreatitis
-
Year
2024
-
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
-
Authors
Wenbin Liu, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT5 inhibits glycolysis and nasal type extranodal NK/T cell lymphoma cell proliferation by catalyzing the desuccinylation of glucose-6-phosphate isomerase
-
Year
2024
-
Journal
Translational Oncology
-
Authors
Tiansheng Wang, et al.
-
Applications
Unspecified
-
Reactivity
-
Importance of benzoyltransferase GcnE and lysine benzoylation of alcohol dehydrogenase AdhB in pathogenesis and aflatoxin production in Aspergillus flavus
-
Year
2024
-
Journal
mBio
-
Authors
Xuan Chen, et al.
-
Applications
Unspecified
-
Reactivity
-
Sirtuin-5 Is Recruited to Hepatic Peroxisomes in Mice Fed Dodecanedioic Acid but Has Little Impact on the Peroxisomal Succinylome
-
Year
2024
-
Journal
Biomolecules
-
Authors
Yuxun Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
Desuccinylation of Inosine-5´-monophosphate Dehydrogenase 1 by SIRT5 Promotes Tumor Cell Proliferation
-
Year
2024
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
-
Authors
Chang Xu, et al.
-
Applications
Unspecified
-
Reactivity
-
Nucleolin Malonylation as a Nuclear-Cytosol Signal Exchange Mechanism to Drive Cell Proliferation in Hepatocarcinoma by Enhancing AKT Translation
-
Year
2024
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
-
Authors
Liang Sun, et al.
-
Applications
Unspecified
-
Reactivity
-
Antitumorigenic potential of Lactobacillus-derived extracellular vesicles: p53 succinylation and glycolytic reprogramming in intestinal epithelial cells via SIRT5 modulation
-
Year
2024
-
Journal
CELL BIOLOGY AND TOXICOLOGY
-
Authors
Zhang Jingbo, et al.
-
Applications
Unspecified
-
Reactivity
-
Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma
-
Year
2024
-
Journal
Cell Metabolism
-
Authors
Guanzhang Li, et al.
-
Applications
Unspecified
-
Reactivity
-
Global lysine succinylation analysis unveils post-translational regulation effect on phenylpropanoid metabolism remodeling during Lonicera japonica flower development
-
Year
2024
-
Journal
PLANT PHYSIOLOGY AND BIOCHEMISTRY
-
Authors
Yao Chen, et al.
-
Applications
Unspecified
-
Reactivity
-
Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation
-
Year
2024
-
Journal
Theranostics
-
Authors
Xiao-Yi Xiong, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT7 Inhibits Melanin Synthesis of PIG1 and PIG3V by Suppressing the Succinylation of EZR
-
Year
2024
-
Journal
Clinical Cosmetic and Investigational Dermatology
-
Authors
Yuehong Ma, et al.
-
Applications
Unspecified
-
Reactivity
-
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
-
Year
2024
-
Journal
Cell Metabolism
-
Authors
Jian Zhou, et al.
-
Applications
Unspecified
-
Reactivity
-
Astragaloside IV inhibits cell viability and glycolysis of hepatocellular carcinoma by regulating KAT2A-mediated succinylation of PGAM1
-
Year
2024
-
Journal
BMC CANCER
-
Authors
Zhu Yuanzhang, et al.
-
Applications
Unspecified
-
Reactivity
-
Succinylation of 14–3–3 theta by CPT1A promotes survival and paclitaxel resistance in nasal type extranodal natural killer/T-cell lymphoma
-
Year
2024
-
Journal
Translational Oncology
-
Authors
Xiao Cui, et al.
-
Applications
Unspecified
-
Reactivity
-
Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
-
Year
2024
-
Journal
iScience
-
Authors
Taolin Yuan, et al.
-
Applications
Unspecified
-
Reactivity
-
Mitochondrial glycerol 3-phosphate dehydrogenase deficiency exacerbates lipotoxic cardiomyopathy
-
Year
2024
-
Journal
iScience
-
Authors
Hua Qu, et al.
-
Applications
Unspecified
-
Reactivity
-
Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation
-
Year
2024
-
Journal
Redox Biology
-
Authors
Maoxiong Wu, et al.
-
Applications
Unspecified
-
Reactivity
-
Proteome, lysine acetylome and succinylome identify post-translational modification of STAT1 as a novel drug target in silicosis
-
Year
2024
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
-
Authors
Tiantian Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
Protein acylations induced by a ketogenic diet demonstrate diverse patterns depending on organs and differ between histones and global proteins
-
Year
2024
-
Journal
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
-
Authors
Minami Ito, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT5 promote malignant advancement of chordoma by regulating the desuccinylation of c-myc
-
Year
2024
-
Journal
BMC CANCER
-
Authors
Jiang Minghui, et al.
-
Applications
Unspecified
-
Reactivity
-
Sirtuin 5 regulates acute myeloid leukemia cell viability and apoptosis by succinylation modification of glycine decarboxylase
-
Year
2024
-
Journal
Open Life Sciences
-
Authors
Jun Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation
-
Year
2024
-
Journal
Cell Death & Disease
-
Authors
Dong Na, et al.
-
Applications
Unspecified
-
Reactivity
-
Regulation of urea cycle by reversible high-stoichiometry lysine succinylation
-
Year
2024
-
Journal
Nature Metabolism
-
Authors
Zhang Ran, et al.
-
Applications
Unspecified
-
Reactivity
-
Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart
-
Year
2024
-
Journal
Scientific Reports
-
Authors
Ketema Ezra B., et al.
-
Applications
Unspecified
-
Reactivity
-
Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner
-
Year
2023
-
Journal
CELL RESEARCH
-
Authors
Liao Long, et al.
-
Applications
Unspecified
-
Reactivity
-
HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation
-
Year
2023
-
Journal
Cell Discovery
-
Authors
Li Jialun, et al.
-
Applications
Unspecified
-
Reactivity
-
Lysine 2-Hydroxyisobutyrylation- and Succinylation-Based Pathways Act Inside Chloroplasts to Modulate Plant Photosynthesis and Immunity
-
Year
2023
-
Journal
Advanced Science
-
Authors
Bin Chen, et al.
-
Applications
Unspecified
-
Reactivity
-
Succinate metabolism and membrane reorganization drives the endotheliopathy and coagulopathy of traumatic hemorrhage
-
Year
2023
-
Journal
Science Advances
-
Authors
Sarah Abdullah, et al.
-
Applications
Unspecified
-
Reactivity
-
Histone malonylation is regulated by SIRT5 and KAT2A
-
Year
2023
-
Journal
iScience
-
Authors
Ran Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
The Deacylase Sirtuin 5 Reduces Malonylation in Non-mitochondrial Metabolic Pathways in Diabetic Kidney Disease
-
Year
2023
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
-
Authors
Judy Baek, et al.
-
Applications
Unspecified
-
Reactivity
-
Heptanoic and medium branched-chain fatty acids as anaplerotic treatment for medium chain acyl-CoA dehydrogenase deficiency
-
Year
2023
-
Journal
MOLECULAR GENETICS AND METABOLISM
-
Authors
Anuradha Karunanidhi, et al.
-
Applications
Unspecified
-
Reactivity
-
Global proteomic analysis reveals lysine succinylation contributes to the pathogenesis of aortic aneurysm and dissection
-
Year
2023
-
Journal
Journal of Proteomics
-
Authors
Hongwei Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
Acylation of the Rat Brain Proteins is Affected by the Inhibition of Pyruvate Dehydrogenase in vivo
-
Year
2023
-
Journal
BIOCHEMISTRY-MOSCOW
-
Authors
Aleshin Vasily A., et al.
-
Applications
Unspecified
-
Reactivity
-
Tandem mass tag-based quantitative proteomic analysis identification of succinylation related proteins in pathogenesis of thoracic aortic aneurysm and aortic dissection
-
Year
2023
-
Journal
PeerJ
-
Authors
Yu Zhang, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration
-
Year
2023
-
Journal
CELL DEATH AND DIFFERENTIATION
-
Authors
Teng Peng, et al.
-
Applications
Unspecified
-
Reactivity
-
Dimethyl Malonate Protects the Lung in a Murine Model of Acute Respiratory Distress Syndrome
-
Year
2023
-
Journal
Journal of Trauma and Acute Care Surgery
-
Authors
Taghavi Sharven, et al.
-
Applications
Unspecified
-
Reactivity
-
SUCLG2 Regulates Mitochondrial Dysfunction through Succinylation in Lung Adenocarcinoma
-
Year
2023
-
Journal
Advanced Science
-
Authors
Qifan Hu, et al.
-
Applications
Unspecified
-
Reactivity
-
Succinylation proteomic analysis identified differentially expressed succinylation sites affecting porcine muscle fiber type function
-
Year
2023
-
Journal
Food Chemistry-X
-
Authors
Xiaofan Tan, et al.
-
Applications
Unspecified
-
Reactivity
-
Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency
-
Year
2023
-
Journal
Redox Biology
-
Authors
Gerardo G. Piroli, et al.
-
Applications
Unspecified
-
Reactivity
-
Inhibition of integrin receptors reduces extracellular matrix levels, ameliorating benign prostate hyperplasia
-
Year
2023
-
Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
-
Authors
Chengfei Yang, et al.
-
Applications
Unspecified
-
Reactivity
-
LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer
-
Year
2023
-
Journal
CELL DEATH AND DIFFERENTIATION
-
Authors
Shi Liang, et al.
-
Applications
Unspecified
-
Reactivity
-
Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
-
Year
2023
-
Journal
Cell Reports
-
Authors
Huanyi Cao, et al.
-
Applications
Unspecified
-
Reactivity
-
The deacylase sirtuin 5 reduces malonylation in nonmitochondrial metabolic pathways in diabetic kidney disease
-
Year
2023
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
-
Authors
Judy Baek, et al.
-
Applications
Unspecified
-
Reactivity
-
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
-
Year
2023
-
Journal
Frontiers of Medicine
-
Authors
Xu Yanhong, et al.
-
Applications
Unspecified
-
Reactivity
-
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer’s disease
-
Year
2022
-
Journal
Nature Communications
-
Authors
Yang Yun, et al.
-
Applications
Unspecified
-
Reactivity
-
Nuclear Condensation of CDYL Links Histone Crotonylation and Cystogenesis in Autosomal Dominant Polycystic Kidney Disease
-
Year
2022
-
Journal
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
-
Authors
Dang Lin, et al.
-
Applications
Unspecified
-
Reactivity
-
Operation of a TCA cycle subnetwork in the mammalian nucleus
-
Year
2022
-
Journal
Science Advances
-
Authors
Eleni Kafkia, et al.
-
Applications
Unspecified
-
Reactivity
-
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis
-
Year
2022
-
Journal
EMBO JOURNAL
-
Authors
Qichao Huang, et al.
-
Applications
Unspecified
-
Reactivity
-
Succinyl-CoA Synthetase Deficiency in Mouse Forebrain Results in Hyper-Succinylation With Perturbed Neuronal Transcriptional Regulation and Metabolism
-
Year
2022
-
Journal
Cell Reports
-
Authors
Anderson Makayla Suzanne, et al.
-
Applications
Unspecified
-
Reactivity
-
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer
-
Year
2022
-
Journal
ACTA PHARMACOLOGICA SINICA
-
Authors
Wang Yu-fei, et al.
-
Applications
Unspecified
-
Reactivity
-
Phosphonate Inhibitors of Pyruvate Dehydrogenase Perturb Homeostasis of Amino Acids and Protein Succinylation in the Brain
-
Year
2022
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
-
Authors
Artem V. Artiukhov, et al.
-
Applications
Unspecified
-
Reactivity
-
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion
-
Year
2022
-
Journal
Neural Regeneration Research
-
Authors
Huang Lin-Yan, et al.
-
Applications
Unspecified
-
Reactivity
-
A suppressor of dioxygenase inhibition in a yeast model of SDH deficiency
-
Year
2022
-
Journal
ENDOCRINE-RELATED CANCER
-
Authors
William Beimers, et al.
-
Applications
Unspecified
-
Reactivity
-
KAT2A Promotes Hepatitis B Virus Transcription and Replication Through Epigenetic Regulation of cccDNA Minichromosome
-
Year
2022
-
Journal
Frontiers in Microbiology
-
Authors
Qin Yi-Ping, et al.
-
Applications
Unspecified
-
Reactivity
-
Protein succinylation associated with the progress of hepatocellular carcinoma
-
Year
2022
-
Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
-
Authors
Wenhui Bai, et al.
-
Applications
Unspecified
-
Reactivity
-
Proteome-wide analyses reveal diverse functions of protein acetylation and succinylation modifications in fast growing stolons of bermudagrass (Cynodon dactylon L.)
-
Year
2022
-
Journal
BMC PLANT BIOLOGY
-
Authors
Zhang Bing, et al.
-
Applications
Unspecified
-
Reactivity
-
Sirt5-mediated desuccinylation of OPTN protects retinal ganglion cells from autophagic flux blockade in diabetic retinopathy
-
Year
2022
-
Journal
Cell Death Discovery
-
Authors
Zhang Ye, et al.
-
Applications
Unspecified
-
Reactivity
-
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
-
Year
2022
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
-
Authors
Dhaval P. Bhatt, et al.
-
Applications
Unspecified
-
Reactivity
-
The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A
-
Year
2022
-
Journal
BIOCHEMISTRY
-
Authors
Ananya Anmangandla, et al.
-
Applications
Unspecified
-
Reactivity
-
NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
-
Year
2021
-
Journal
Cell Metabolism
-
Authors
Mi Kyung Park, et al.
-
Applications
Unspecified
-
Reactivity
-
Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage
-
Year
2021
-
Journal
CELL DEATH AND DIFFERENTIATION
-
Authors
Liu Xing, et al.
-
Applications
Unspecified
-
Reactivity
-
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice
-
Year
2021
-
Journal
JOURNAL OF HAZARDOUS MATERIALS
-
Authors
Zijun Peng, et al.
-
Applications
Unspecified
-
Reactivity
-
Deletion of BCATm increases insulin-stimulated glucose oxidation in the heart
-
Year
2021
-
Journal
METABOLISM-CLINICAL AND EXPERIMENTAL
-
Authors
Golam M. Uddin, et al.
-
Applications
Unspecified
-
Reactivity
-
Comprehensive identification of lysine 2-hydroxyisobutyrylated proteins in Ustilaginoidea virens reveals the involvement of lysine 2-hydroxyisobutyrylation in fungal virulence
-
Year
2021
-
Journal
Journal of Integrative Plant Biology
-
Authors
Xiaoyang Chen, et al.
-
Applications
Unspecified
-
Reactivity
-
Cellular carbon stress is a mediator of obesity-associated osteoarthritis development
-
Year
2021
-
Journal
OSTEOARTHRITIS AND CARTILAGE
-
Authors
H. Liu, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT7 restricts HBV transcription and replication through catalyzing desuccinylation of histone H3 associated with cccDNA minichromosome
-
Year
2021
-
Journal
CLINICAL SCIENCE
-
Authors
Yu Hai-Bo, et al.
-
Applications
Unspecified
-
Reactivity
-
Dietary succinate supplementation to maternal mice improves fetal brown adipose tissue development and thermogenesis of female offspring
-
Year
2021
-
Journal
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
-
Authors
Xiangdong Liu, et al.
-
Applications
Unspecified
-
Reactivity
-
Systematic Proteome and Lysine Succinylome Analysis Reveals Enhanced Cell Migration by Hyposuccinylation in Esophageal Squamous Cell Carcinoma
-
Year
2021
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
-
Authors
Zhenchang Guo, et al.
-
Applications
Unspecified
-
Reactivity
-
Preparation of Affinity Purified Antibodies against ε-Glutaryl-Lysine Residues in Proteins for Investigation of Glutarylated Proteins in Animal Tissues
-
Year
2021
-
Journal
Biomolecules
-
Authors
Artem V. Artiukhov, et al.
-
Applications
Unspecified
-
Reactivity
-
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome
-
Year
2021
-
Journal
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
-
Authors
Jessica N. Peoples, et al.
-
Applications
Unspecified
-
Reactivity
-
Dysregulation of the Sirt5/IDH2 axis contributes to sunitinib resistance in human renal cancer cells
-
Year
2021
-
Journal
FEBS Open Bio
-
Authors
Liang Meng, et al.
-
Applications
Unspecified
-
Reactivity
-
Skeletal muscle of torpid Richardson's ground squirrels (Urocitellus richardsonii) exhibits a less active form of citrate synthase associated with lowered lysine succinylation
-
Year
2021
-
Journal
CRYOBIOLOGY
-
Authors
Stuart R. Green, et al.
-
Applications
Unspecified
-
Reactivity
-
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation
-
Year
2020
-
Journal
Cell Metabolism
-
Authors
Rami Al Batran, et al.
-
Applications
Unspecified
-
Reactivity
-
Protein Hyperacylation Links Mitochondrial Dysfunction with Nuclear Organization
-
Year
2020
-
Journal
MOLECULAR CELL
-
Authors
Smestad John, et al.
-
Applications
Unspecified
-
Reactivity
-
Repression of P53 Function by SIRT5-Mediated Desuccinylation at Lysine 120
-
Year
2020
-
Journal
Cell Reports
-
Authors
Liu Xing, et al.
-
Applications
Unspecified
-
Reactivity
-
SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose-derived mesenchymal stem cells via metabolic switching
-
Year
2020
-
Journal
Clinical and Translational Medicine
-
Authors
Tiantong Ou, et al.
-
Applications
Unspecified
-
Reactivity
-
Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer
-
Year
2020
-
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
-
Authors
Li Xiang, et al.
-
Applications
Unspecified
-
Reactivity
-
Increased protein propionylation contributes to mitochondrial dysfunction in liver cells and fibroblasts, but not in myotubes
-
Year
2020
-
Journal
JOURNAL OF INHERITED METABOLIC DISEASE
-
Authors
Bart Lagerwaard, et al.
-
Applications
Unspecified
-
Reactivity
-
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice
-
Year
2020
-
Journal
Scientific Reports
-
Authors
Goetzman Eric S., et al.
-
Applications
Unspecified
-
Reactivity
-
An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells
-
Year
2020
-
Journal
Scientific Reports
-
Authors
Yuan Taolin, et al.
-
Applications
Unspecified
-
Reactivity
-
Nucleotide-binding sites can enhance N-acylation of nearby protein lysine residues
-
Year
2020
-
Journal
Scientific Reports
-
Authors
James Andrew M., et al.
-
Applications
Unspecified
-
Reactivity
-
Succinylation at a key residue of FEN1 is involved in the DNA damage response to maintain genome stability
-
Year
2020
-
Journal
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
-
Authors
Rongyi Shi, et al.
-
Applications
Unspecified
-
Reactivity
-
Systematic analysis of lysine acetylome and succinylome reveals the correlation between modification of H2A.X complexes and DNA damage response in breast cancer
-
Year
2020
-
Journal
ONCOLOGY REPORTS
-
Authors
Xiuli Gao, et al.
-
Applications
Unspecified
-
Reactivity
-
Regulation of the α-ketoglutarate dehydrogenasecomplex during hibernation in a small mammal, the Richardson's ground squirrel (Urocitellus richardsonii)
-
Year
2020
-
Journal
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
-
Authors
Stuart R. Green, et al.
-
Applications
Unspecified
-
Reactivity
-
A Qualitative Proteome-Wide Lysine Succinylation Profiling of Tea Revealed its Involvement in Primary Metabolism
-
Year
2020
-
Journal
MOLECULAR BIOLOGY
-
Authors
Qiu C., et al.
-
Applications
Unspecified
-
Reactivity
-
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
-
Year
2019
-
Journal
MOLECULAR CELL
-
Authors
GuoXiao Wang, et al.
-
Applications
Unspecified
-
Reactivity
-
Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI
-
Year
2019
-
Journal
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
-
Authors
Chiba Takuto, et al.
-
Applications
Unspecified
-
Reactivity
-
Targeting oxidative pentose phosphate pathway prevents recurrence in mutant Kras colorectal carcinomas
-
Year
2019
-
Journal
PLOS BIOLOGY
-
Authors
WenChao Gao, et al.
-
Applications
Unspecified
-
Reactivity
-
Comprehensive Analysis of the Lysine Succinylome and Protein Co-modifications in Developing Rice Seeds *
-
Year
2019
-
Journal
MOLECULAR & CELLULAR PROTEOMICS
-
Authors
Xiaoxi Meng, et al.
-
Applications
Unspecified
-
Reactivity
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Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism
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Year
2019
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Hadi R. Ali, et al.
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Applications
Unspecified
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Reactivity
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Lead-mediated inhibition of lysine acetylation and succinylation causes reproductive injury of the mouse testis during development
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Year
2019
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Journal
TOXICOLOGY LETTERS
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Authors
Qiangzhen Yang, et al.
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Applications
Unspecified
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Reactivity
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Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans
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Year
2019
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Journal
PROTEOMICS
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Authors
Congli Zhou, et al.
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Applications
Unspecified
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Reactivity
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Quantitative proteomics of changes in succinylated proteins expression profiling in left appendages tissue from valvular heart disease patients with atrial fibrillation
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Year
2019
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Journal
CLINICA CHIMICA ACTA
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Authors
Fan Bai, et al.
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Applications
Unspecified
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Reactivity
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A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline
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Year
2018
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Journal
Cell Metabolism
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Authors
Mariana G. Tarragó, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner
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Year
2018
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Journal
Nature Communications
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Authors
Wang Yun-Qian, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice
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Year
2018
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Journal
EBioMedicine
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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Chromatin Succinylation Correlates with Active Gene Expression and Is Perturbed by Defective TCA Cycle Metabolism
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Year
2018
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Journal
iScience
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Authors
John Smestad, et al.
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Applications
Unspecified
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Reactivity
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Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products
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Year
2018
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Journal
Cell Chemical Biology
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Authors
Jun-Yu Xu, et al.
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Applications
Unspecified
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Reactivity
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SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer
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Year
2018
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Journal
Molecular Oncology
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Authors
Liang Shi, et al.
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Applications
Unspecified
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Reactivity
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Lysine Succinylation Contributes to Aflatoxin Production and Pathogenicity in Aspergillus flavus*
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Year
2018
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Silin Ren, et al.
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Applications
Unspecified
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Reactivity
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CPT1A‐mediated succinylation of S100A10 increases human gastric cancer invasion
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Year
2018
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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Authors
Chao Wang, et al.
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Applications
Unspecified
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Reactivity
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Systematic Identification and Analysis of Lysine Succinylation in Strawberry Stigmata
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Year
2018
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Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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Authors
Xianping Fang, et al.
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Applications
Unspecified
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Reactivity
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Cadmium inhibits lysine acetylation and succinylation inducing testicular injury of mouse during development
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Year
2018
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Journal
TOXICOLOGY LETTERS
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Authors
Qiangzhen Yang, et al.
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Applications
Unspecified
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Reactivity
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Purification of carbamoyl phosphate synthetase 1 (CPS1) from wood frog (Rana sylvatica) liver and its regulation in response to ice-nucleation and subsequent whole-body freezing
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Year
2018
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Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
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Authors
Green Stuart R., et al.
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Applications
Unspecified
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Reactivity
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Tissue distribution, subcellular localization, and enzymatic activity analysis of human SIRT5 isoforms
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Year
2018
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Journal
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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CPT1A-mediated succinylation of S100A10 increases human gastric cancer invasion
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Year
2018
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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Authors
Chao Wang, et al.
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Applications
Unspecified
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Reactivity
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A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation
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Year
2017
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Journal
Cell Metabolism
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Authors
Gregory R. Wagner, et al.
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Applications
Unspecified
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Reactivity
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Characterization of histone acylations links chromatin modifications with metabolism
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Year
2017
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Journal
Nature Communications
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Authors
Simithy Johayra, et al.
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Applications
Unspecified
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Reactivity
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Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II
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Year
2017
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Journal
Cell Reports
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Authors
Andrew M. James, et al.
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Applications
Unspecified
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Reactivity
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Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain
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Year
2017
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Yuxun Zhang, et al.
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Applications
Unspecified
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Reactivity
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The Mammalian Malonyl-CoA Synthetase ACSF3 Is Required for Mitochondrial Protein Malonylation and Metabolic Efficiency
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Year
2017
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Journal
Cell Chemical Biology
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Authors
Caitlyn E. Bowman, et al.
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Applications
Unspecified
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Reactivity
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Site-Specific Installation of Succinyl Lysine Analog into Histones Reveals the Effect of H2BK34 Succinylation on Nucleosome Dynamics
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Year
2017
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Journal
Cell Chemical Biology
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Authors
Yihang Jing, et al.
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Applications
Unspecified
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Reactivity
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SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability
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Year
2016
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Journal
Nature Communications
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Authors
Li Lei, et al.
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Applications
Unspecified
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Reactivity
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Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function
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Year
2016
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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Authors
Sushabhan Sadhukhan, et al.
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Applications
Unspecified
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Reactivity
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NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice
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Year
2016
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Journal
Cell Reports
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Authors
Jonathan B. Lin, et al.
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Applications
Unspecified
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Reactivity
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SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense
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Year
2016
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Journal
EMBO REPORTS
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Authors
Lisha Zhou, et al.
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Applications
Unspecified
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Reactivity
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Succinyl-proteome profiling of a high taxol containing hybrid Taxus species (Taxus × media) revealed involvement of succinylation in multiple metabolic pathways
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Year
2016
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Journal
Scientific Reports
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Authors
Shen Chenjia, et al.
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Applications
Unspecified
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Reactivity
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Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation
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Year
2016
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Journal
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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Authors
Hala Guedouari, et al.
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Applications
Unspecified
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Reactivity
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Prediction of Protein Lysine Acylation by Integrating Primary Sequence Information with Multiple Functional Features
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Year
2016
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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Systematic Analysis of the Lysine Succinylome in Candida albicans
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Year
2016
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Hailin Zheng, et al.
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Applications
Unspecified
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Reactivity
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Global Proteome Analyses of Lysine Acetylation and Succinylation Reveal the Widespread Involvement of both Modification in Metabolism in the Embryo of Germinating Rice Seed
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Year
2016
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Dongli He, et al.
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Applications
Unspecified
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Reactivity
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The Role of Mitochondrial Non-Enzymatic Protein Acylation in Ageing
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Year
2016
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Journal
PLoS One
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Authors
Shin Yee Hong, et al.
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Applications
Unspecified
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Reactivity
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
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Year
2015
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Journal
Nature Communications
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Authors
Madsen Christian T., et al.
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Applications
Unspecified
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Reactivity
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Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis
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Year
2015
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Mingkun Yang, et al.
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Applications
Unspecified
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Reactivity
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Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury
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Year
2015
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Journal
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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Authors
Jennifer A. Boylston, et al.
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Applications
Unspecified
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Reactivity
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Succinylome Analysis Reveals the Involvement of Lysine Succinylation in Metabolism in Pathogenic Mycobacterium tuberculosis*[S]
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Year
2015
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Mingkun Yang, et al.
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Applications
Unspecified
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Reactivity
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Lysine Malonylation Is Elevated in Type 2 Diabetic Mouse Models and Enriched in Metabolic Associated Proteins *
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Year
2014
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Journal
MOLECULAR & CELLULAR PROTEOMICS
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Authors
Yipeng Du, et al.
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Applications
Unspecified
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Reactivity
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Systematic Identification of the Lysine Succinylation in the Protozoan Parasite Toxoplasma gondii
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Year
2014
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Journal
JOURNAL OF PROTEOME RESEARCH
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Authors
Xiaolong Li, et al.
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Applications
Unspecified
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Reactivity
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Pigment Epithelium-Derived Factor (PEDF) Suppresses IL-1β-Mediated c-Jun N-Terminal Kinase (JNK) Activation to Improve Hepatocyte Insulin Signaling
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Year
2014
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Journal
ENDOCRINOLOGY
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Authors
Gattu Arijeet K., et al.
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Applications
Unspecified
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Reactivity
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Succinate is an inflammatory signal that induces IL-1β through HIF-1α
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Year
2013
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Journal
NATURE
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Authors
Tannahill G. M., et al.
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Applications
Unspecified
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Reactivity
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Widespread and Enzyme-independent Nϵ-Acetylation and Nϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix *♦
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Year
2013
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
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Authors
Gregory R. Wagner, et al.
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Applications
Unspecified
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Reactivity
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Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation
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Year
2013
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Journal
Cell Reports
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Authors
Brian T. Weinert, et al.
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Applications
Unspecified
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Reactivity