Clone Number: JRMR-10400-15
Host: Rabbit Clonality: Monoclonal
Applications： WB IHC-P ICC/IF FC
Reactivity: Human, Mouse, Rat
Synonyms: FOR, SDR41C1, WOX1
Shipping: Ambient temperature
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| Isotype | IgG |
| Conjugate | Unconjugated |
| Synonyms | FOR, SDR41C1, WOX1 |
| UniProt ID | |
| Immunogen | |
| MW (kDa) | |
| Specificity |
| Applications | Dilution | Recommended Species |
|---|---|---|
| WB | 1:500-1:2000 | Human，Mouse，Rat |
| IHC-P | 1:50-1:100 | Human，Rat |
| ICC/IF | 1:200-1:500 | Human |
| FC | 1:50 | Human |
| Purity | Protein A purified |
| Constituents | PBS, Glycerol, BSA |
| Storage | Store at -20°C. Avoid freeze/thaw cycles. |
| Stability | Stable for 12 months from date of receipt/reconstitution. |
Background
Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Cellular location
Cytoplasm, Nucleus
| WB | |
|---|---|
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Blocking buffer: 5% NFDM/TBST |
| IHC-P | |
|---|---|
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Tissue: Human testis |
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Tissue: Human cerebrum |
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Tissue: Rat cerebrum |
| ICC/IF | |
|---|---|
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Cell line: MCF7 |
| FC | |
|---|---|
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Cell line: MCF-7 |
Research Use
For research use only, not for use in diagnostic procedures.
