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Firstly, proteins were searched against the STRING database for protein-protein interactions. Then, the protein-protein interactions network was visualized by Cytoscape software. In order to further analyze the interactive network, the MCODE plug-in is used to mine the modules with high connectivity in the network, and then annotate the functions of the modules, marking the key biological processes that each module may be involved in.
Association analysis network of modification proteins. The point in the network represents the protein, the color represents the type of protein modification, and the size of the point represents the number of interacting proteins. Two highly connected modules and their biological functions are highlighted in the network diagram.
PML hyposumoylation is responsible for the resistance of pancreatic cancer-2019-The FASEB Journal
Landscapes of Protein Posttranslational Modifications of African Trypanosoma Parasites-2020-iScience
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